Deletions and Amplifications of Tandemly Arranged Ribosomal 5s Genes Internal to a P Element Occur at a High Rate in a Dysgenic Context
AUTOR(ES)
Paques, F.
RESUMO
We observed unusual kinds of rearrangements within tandemly clustered 5S genes internal to a P element in dysgenic context. Rearranged P transposons, initially containing eight 5S genes, were found to display discrete numbers of 5S genes, from 4 up to 17 units. Precise deletions and amplifications occurred at a high rate (40%), at both original and new insertion sites. These events can be explained by a ``cut and paste'' transposition model. Possible links between rearrangements due to dysgenic-like processes and concerted evolution are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1205649Documentos Relacionados
- Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae.
- Oocyte and somatic 5S ribosomal RNA and 5S RNA encoding genes in Xenopus tropicalis.
- Ribosomal 5S genes in relation to C-value in amphibians.
- An alternative protein factor which binds the internal promoter of Xenopus 5S ribosomal RNA genes.
- Changes in chromatin structure accompany modulation of the rate of transcription of 5S ribosomal genes in Tetrahymena.