Delivery of Short Hairpin RNA Sequences by Using a Replication-Competent Avian Retroviral Vector
AUTOR(ES)
Bromberg-White, Jennifer L.
FONTE
American Society for Microbiology
RESUMO
While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=387706Documentos Relacionados
- Tissue-Specific Transcriptional Targeting of a Replication-Competent Retroviral Vector
- Expression of a molecularly cloned human c-src oncogene by using a replication-competent retroviral vector.
- Construction and Characterization of a Replication-Competent Retroviral Shuttle Vector Plasmid
- Regulated Gene Expression in the Chicken Embryo by Using Replication-Competent Retroviral Vectors
- Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector.
