DetecÃÃo da atividade antifÃngica de extratos de plantas do manguezal de Vila Velha, Itamaracà - PE

AUTOR(ES)
DATA DE PUBLICAÇÃO

2004

RESUMO

The use of plants extracts with antimicrobial properties have great significance in the therapeutic treatment. In Brazil, only 5% species by plants were studied their phytochemistry and one percent these plants were evaluated about biologicals aspects. This work evaluated antifungal activity of leaves and barks from Avicennia sp., Conocarpus erectus, Laguncularia racemosa and Rhizophora mangle colleted in the Paripe river estuary (Vila Velha, ItamaracÃ-PE), against dermatophytes and yeasts. After dryer, the plants were reduced powder and submited many extractions with MeOH. Screening phytochemical was carried out in order to identify the chemicals groups presents these plants. The antifungal activity test of extracts were performed by disk diffusion and minimum inhibition concentration (MIC) methods. The microorganisms used: yeasts (Candida albicans, C. parakrusei, C. tropicalis, C. glabrata, C. parapsilosis, Trichosporon beigelii and T. pullulans) and dermatophytes (Epidermophyton floccosum, Microsporum gypseum, Trichophyton mentagrophytes and T. rubrum). Screening phytochemical showed the presence of flavonoids, terpenes, steroids and tannins these plants. Tannis represented the group principal existent and bark of sample 1 from Avicennia showed terpenes and steroids with high intensity. For yeasts, in disk diffusion test, was active bark extracts of sample 1 from Avicennia, C. erectus and R. mangle, the leaves from L. racemosa. The dermatophytes were sensible all extracts, execpt sample 2 from Avicennia. The disk diffusion test C. albicans was specie more resistence than T. pullulans was more sensible, followed by C. parakrusei, C. glabrata and C. parapsilosis. For dermatophytes, E. floccosum was more sensible, followed by T. rubrum, T. menta grophytes and M. gypseum. Minimum inhibition concentration determination of yeasts species T. beigelii, T. pullulans, C. parakrusei and C. parapsilosis were more susceptible, with MIC 15,625 mg/mL. The dermatophyte fungi, E. floccosum was more susceptible, showed MIC 15,625 mg/mL, while M. gypseum was more resistence with MIC 1000 mg/mL. This work show that the species studied, in special, bark of sample 1 from Avicennia, has great potential antifungal and study posteriors must be conducted to isolate the compounds actives

ASSUNTO(S)

antifungal activity atividade antifÃngica yeasts mangrove dermatÃfitos manguezal micologia dermatophytes leveduras

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