Detecting DNA regulatory motifs by incorporating positional trends in information content
AUTOR(ES)
Kechris, Katherina J
FONTE
BioMed Central
RESUMO
On the basis of the observation that conserved positions in transcription factor binding sites are often clustered together, a simple extension to the model-based motif discovery method is proposed. Examples with both simulated and real data show that this extension helps discover motifs as the data become noisier or when there is a competing false motif.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=463320Documentos Relacionados
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