Detection and Sequence Analysis of Hepatitis B Virus Integration in Peripheral Blood Mononuclear Cells

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

A PCR-based technique was used to detect hepatitis B virus (HBV) integration in peripheral blood mononuclear cells from patients with chronic hepatitis B. Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients.

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