Detection of antigenically distinct rotaviruses from infants.
AUTOR(ES)
Dimitrov, D H
RESUMO
Antigenically distinct rotaviruses, i.e., viruses morphologically identical to conventional rotaviruses by electron microscopy, yet lacking the common group antigen(s) detected by an enzyme-linked immunosorbent assay, were found in 2 of 51 fecal samples from Bulgarian infants with rotavirus gastroenteritis. These antigenically distinct viruses contained 11 segments of double-stranded RNA, but they demonstrated a unique RNA migration profile after electrophoresis of the genome RNA in polyacrylamide gels. This report confirms the presence of a new group of rotaviruses in humans. The significance of these viruses is currently unknown, and specific diagnostic tests must be developed for epidemiological studies to determine their role as human and veterinary pathogens and to evaluate their impact on proposed vaccine development programs.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=264672Documentos Relacionados
- Distinct populations of rotaviruses circulating among neonates and older infants.
- Differentiating minor from serious illness in infants.
- Transfer of antirotaviral antibodies from mothers to their infants.
- Stereoacuity of human infants.
- Effect of fibronectin on adherence of neutrophils from newborn infants.