Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.
AUTOR(ES)
Brownell, E
RESUMO
A portion of the human cellular homolog of v-rel, the transforming gene of the leukemogenic retrovirus reticuloendotheliosis virus, strain T, was used to survey RNAs from several mouse tissues, selected lymphocyte populations, and hematopoietic cell lines for c-rel expression. Relatively high levels of a high-molecular-weight transcript were observed in peripheral B and T cells, whereas lower levels were detectable in functionally immature thymocytes. These results suggested that, unlike c-myb and c-ets, the c-rel proto-oncogene plays a role in later stages of lymphocyte differentiation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=365210Documentos Relacionados
- Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines.
- Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.
- Extracellular superoxide dismutase in human tissues and human cell lines.
- Expression of two different forms of fibroblast growth factor receptor 1 in different mouse tissues and cell lines.
- Bcr/Abl expression stimulates integrin function in hematopoietic cell lines.
