Detection of determinant genes and diagnostic via Item Response Theory

AUTOR(ES)

Tavares, Héliton Ribeiro, Andrade, Dalton Francisco de, Pereira, Carlos Alberto de Bragança

FONTE

Genetics and Molecular Biology

DATA DE PUBLICAÇÃO

2004

RESUMO

This work presents a method to analyze characteristics of a set of genes that can have an influence in a certain anomaly, such as a particular type of cancer. A measure is proposed with the objective of diagnosing individuals regarding the anomaly under study and some characteristics of the genes are analyzed. Maximum likelihood equations for general and particular cases are presented.

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