Detection of DNA Synthesis in Intact Organisms with Positron-Emitting [Methyl-11C]Thymidine
AUTOR(ES)
Christman, David
RESUMO
11CO2 produced in the Brookhaven 152-cm cyclotron was converted to formaldehyde, which in turn was used for the enzymatic conversion of deoxyuridine-5′-phosphate to [11C]thymidylate. Enzymatic treatment of the nucleotide with alkaline phosphatase gave [11C]thymidine.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=426610Documentos Relacionados
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