Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4.

AUTOR(ES)

Ramaiah, D

RESUMO

The specific reaction of potassium permanganate with thymine in single-stranded DNA was employed to analyze thymine [2+2] dimer repair in DNA and in DNA/peptide nucleic acid hybrid duplexes. This simple and highly sensitive chemical assay is convenient for monitoring repair of thymine dimers in oligonucleotides.

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