Development of Radiation Resistance in Salmonella Cultures1

AUTOR(ES)

Licciardello, J. J.

RESUMO

Cultures of Salmonella subjected to repeated cycles of gamma-irradiation and subculture developed radiation resistance sooner at a low cycling dose (∼1% survival) compared to a high cycling dose (∼0.001% survival). Radioresistant cells in a population of radiosensitive cells of Salmonella newport or S. typhimurium could be selected by the double-irradiation plate method. The frequency of radioresistant cells in a population of S. newport was found to be about 1 per 8.9 million. Radio-resistant cells obtained by cyclic irradiation and subculture were larger (plumper) than the parent strain and showed a marked pleomorphism.

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