Diagnosis of toxoplasma infection in cardiac transplant recipients using the polymerase chain reaction.
AUTOR(ES)
Holliman, R
RESUMO
Cardiac biopsy samples taken from transplant recipients around the time of primary toxoplasma infection were investigated by conventional histology and amplification of the P30 gene of Toxoplasma gondii by the polymerase chain reaction (PCR). Toxoplasma was detected more frequently by PCR than histology which may reflect the enhanced sensitivity of the former technique. Further studies are required to determine the optimal amount of tissue which should be examined by each technique and to develop a PCR assay capable of distinguishing between quiescent infection and active toxoplasmosis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=495073Documentos Relacionados
- Detection of CMV DNA in bone marrow transplant recipients: plasma versus leucocyte polymerase chain reaction.
- Low predictive value of polymerase chain reaction for diagnosis of cytomegalovirus disease in liver transplant recipients.
- Detection of murine typhus infection in fleas by using the polymerase chain reaction.
- Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid.
- Rapid and biologically safe diagnosis of African swine fever virus infection by using polymerase chain reaction.