Differences in Direct Effects of Adrenergic Stimuli on Coronary, Cutaneous, and Muscular Vessels
AUTOR(ES)
Mark, Allyn L.
RESUMO
Direct effects of adrenergic stimuli on coronary vessels in dogs were compared with effects on vessels to skin (hind paw) and skeletal muscle (gracilis muscle) after intravenous administration of practolol (2 mg/kg), a selective myocardial beta receptor blocker which minimized indirect effects of myocardial stimulation on coronary vascular resistance. The left circumflex coronary, cranial tibial, and gracilis arteries were perfused separately but simultaneously at constant flow. Perfusion pressures, left ventricular pressure and dP/dt. and heart rate were recorded. Changes in perfusion pressure to each bed reflected changes in vascular resistance.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=302125Documentos Relacionados
- Responses of coronary vessels to adrenergic stimuli
- Multiple arterial stenoses of unknown aetiology in the coronary, cerebral, and brachial arteries.
- A comparison of the effects of vasodilator stimuli on peripheral resistance vessels in normal subjects and in patients with congestive heart failure
- Direct and reflex effects of nitroglycerin on coronary and left ventricular dynamics in conscious dogs
- Autoradiographic characterization of beta adrenergic receptors in coronary blood vessels and myocytes in normal and ischemic myocardium of the canine heart.