Differential Effects of Gamma Interferon on Chlamydia trachomatis Growth in Polarized and Nonpolarized Human Epithelial Cells in Culture
AUTOR(ES)
Kane, Colleen D.
FONTE
American Society for Microbiology
RESUMO
The effects of gamma interferon (IFN-γ) on Chlamydia trachomatis growth in polarized epithelial cells were examined. The range of IFN-γ concentrations causing aberrant chlamydial growth was wider in polarized than in nonpolarized cultures. Results indicate that chlamydial growth modulation in polarized cells readily leads to persistence and better reflects in vivo conditions.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=108203Documentos Relacionados
- Entry of genital Chlamydia trachomatis into polarized human epithelial cells.
- Differential Sensitivities of Chlamydia trachomatis Strains to Inhibitory Effects of Gamma Interferon
- Inhibition of growth of Chlamydia trachomatis by human gamma interferon.
- Intracellular Tryptophan Pool Sizes May Account for Differences in Gamma Interferon-Mediated Inhibition and Persistence of Chlamydial Growth in Polarized and Nonpolarized Cells
- Effect of interferon on the growth of Chlamydia trachomatis in mouse fibroblasts (L cells).
