Differentiation of a rat mammary cell line in vitro.
AUTOR(ES)
Dulbecco, R
RESUMO
We have studied the development of fusiform (probably related to myoepithelial) cells in Rama 25 cultures [Bennett, D. C. Peachey, L. A., Durbin, H. & Rudland, P. S. (1978) Cell 15, 283--298]; we show that they are generated from special differentiated structures (projections) that contain a rapidly differentiating cell type (F-precursor cells). Clonal sublines isolated from projections develop in several directions under both environmental and genetic control. Some types of differentiation are reversible; others are irreversible. The various cell occurring in vitro may correspond to specific cell types in vivo.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=383229Documentos Relacionados
- Role of Thy-1 antigen in the in vitro differentiation of a rat mammary cell line.
- Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.
- Hormone-dependent differentiation of mammary gland in vitro.
- Thy-1: a differentiation marker of potential mammary myoepithelial cells in vitro.
- Control of differentiation of a mammary cell line by lipids.