Diffusion-based Transport of Nascent Ribosomes in the NucleusV⃞

AUTOR(ES)

Ritland Politz, Joan C.

FONTE

The American Society for Cell Biology

RESUMO

Although the complex process of ribosome assembly in the nucleolus is beginning to be understood, little is known about how the ribosomal subunits move from the nucleolus to the nuclear membrane for transport to the cytoplasm. We show here that large ribosomal subunits move out from the nucleolus and into the nucleoplasm in all directions, with no evidence of concentrated movement along directed paths. Mobility was slowed compared with that expected in aqueous solution in a manner consistent with anomalous diffusion. Once nucleoplasmic, the subunits moved in the same random manner and also sometimes visited another nucleolus before leaving the nucleus.

Documentos Relacionados

• Diffusion-based method for producing density-equalizing maps
• Disk Diffusion-Based Methods for Determining Candida parapsilosis Susceptibility to Anidulafungin
• Spindle Formation in Aspergillus Is Coupled to Tubulin Movement into the NucleusV⃞
• SYNTHESIS OF NASCENT PROTEIN BY RIBOSOMES IN ESCHERICHIA COLI
• Nascent ribosomes from HeLa cells.