Direct Ex Vivo Measurement of CD8+ T-Lymphocyte Responses to Human Parvovirus B19
AUTOR(ES)
Tolfvenstam, T.
FONTE
American Society for Microbiology
RESUMO
Parvovirus B19 is a common human pathogen which can cause severe syndromes, including aplastic anemia and fetal hydrops. The mapping of the first parvovirus B19-derived CD8+ T-lymphocyte epitope is described. This HLA-B35-restricted peptide derives from the nonstructural (NS1) protein and is strongly immunogenic in B19 virus-seropositive donors.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=113948Documentos Relacionados
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