Disseminated aspergillosis

AUTOR(ES)

Burke, B. J.

RESUMO

The history and the clinical and necropsy findings are presented of a patient who died from Aspergillus fumigatus pyaemia occurring as an opportunistic infection complicating a dissecting aortic aneurysm. The diagnosis was made (and treatment instituted) during life: it rested upon repeated isolation of the organism from tracheal aspirations, a positive blood culture and positive serum precipitin reactions to A. fumigatus. Debilitating disease along with large doses of antibiotics and corticosteroids provided the conditions necessary for the normally saphrophytic fungi to become pathogenic. As the therapy for aspergillosis is still ineffective, the danger of prescribing large doses of antibiotics together with corticosteroids is stressed.

Documentos Relacionados

• Disseminated aspergillosis in a patient with ocular reticulum cell sarcoma.
• Efficacy of Voriconazole in a Guinea Pig Model of Disseminated Invasive Aspergillosis
• Disseminated Aspergillosis Caused by Aspergillus ustus in a Patient Following Allogeneic Peripheral Stem Cell Transplantation
• Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice
• Efficacy of cilofungin alone and in combination with amphotericin B in a murine model of disseminated aspergillosis.