Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles.

AUTOR(ES)

Kimura, M

RESUMO

A formula for the distribution of allelic frequencies in a finite population is derived assuming stepwise production of multiple alleles. Monte Carlo experiments were performed to check the validity of the formula, and excellent agreement was obtained between theoretical distribution and experimental results. The formula should be useful for analyzing genetic variability in natural populations that can be detected by electrophoretic methods.

Documentos Relacionados

• Stepwise mutation model and distribution of allelic frequencies in a finite population.
• Maintenance of Genetic Variability under the Pressure of Neutral and Deleterious Mutations in a Finite Population
• Maximum Likelihood Analysis of Population Differences in Allelic Frequencies
• The Age of a Neutral Mutant Persisting in a Finite Population
• A Sampling Theory of Selectively Neutral Alleles in a Subdivided Population