Distribution of Protein Kinase C Isoforms after Infection of Macrophages with Leishmania major
AUTOR(ES)
Pingel, Sabine
FONTE
American Society for Microbiology
RESUMO
We characterized the effects of Leishmania infection on activation-induced translocation of protein kinase C (PKC) isoforms in murine bone marrow-derived macrophages. Although PKC-dependent gene expression was attenuated by infection, the distribution and translocation of PKC isoforms were unaffected. However, subsequent dissociation from membranes was substantially delayed for some isoforms, particularly PKCβ.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=108124Documentos Relacionados
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