DNA and ATP Binding Activities of the Baculovirus DNA Helicase P143
AUTOR(ES)
McDougal, Vivien V.
FONTE
American Society for Microbiology
RESUMO
P143 is a DNA helicase that tightly binds both double-stranded and single-stranded DNA. DNA-protein complexes rapidly dissociated in the presence of ATP and Mg2+. This finding suggests that ATP hydrolysis causes a conformational change in P143 which decreases affinity for DNA. This supports the model of an inchworm mechanism of DNA unwinding.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=114452Documentos Relacionados
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