DOSAGE COMPENSATION FOR ENZYME ACTIVITIES IN Drosophila melanogaster*

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RESUMO

There are certain genes on the sex chromosome of Drosophila for which the female contains twice as many copies as the male. Some of the genes in this group produce the same phenotype in each sex despite the dosage difference and are said, therefore, to manifest dosage compensation. The structural genes for glucose-6-phosphate and 6-phosphogluconate dehydrogenases are located on the sex chromosome. We measured these enzyme activities in normal flies of each sex and in flies bearing fewer or extra copies of these genes.

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