Down's syndrome associated with two Robertsonian translocations, 45,XX,−15,−21,+t(15q21q) and 46,XX,−21,+t(21q21q)

AUTOR(ES)

Atkins, Leonard

RESUMO

A female infant with Down's syndrome was found to be a chromosomal mosaic with two cell lines in both blood and skin cells. One line carried a balanced 15/21 translocation, and the other line was effectively trisomic for chromosome 21 with a 21/21 translocation.

Documentos Relacionados

• Mosaic Down's syndrome with de novo 45,XX,-21,-22,+t(21q;22q)/46,XX,-21,+t(21q;21q) rearrangement.
• An unusual case of mosaic Down's syndrome involving two different Robertsonian translocations.
• Down's Syndrome with 47,XX,+21/47,XX,+mar Mosaicism
• Sibship (21q21q) Translocation Down's Syndrome with Maternal Transmission
• Karyotype 45,XX,−21/46,XX,21q− in an infant with symptoms of G-deletion syndrome I