Effect of ethylene glycol dinitrate on metabolism of catecholamines and on blood pressure reaction to re-exposure

AUTOR(ES)

Minami, Masayasu

RESUMO

Minami, M., Okada, A., Takizawa, A., and Kubota, J. (1972).Brit. J. industr. Med.,29, 321-327. Effect of ethylene glycol dinitrate on metabolism of catecholamines and on blood pressure reaction to re-exposure. Male Donryu rats were divided into two groups. One group was given 65 mg/kg per day of ethylene glycol dinitrate (EGDN) subcutaneously for five days and the other group received the same for 10 days. On the first, second, third, fourth, and fifth days after the last injection of EGDN catecholamines were estimated in the heart, brain, and adrenals and plasma 11-hydroxycorticosteroids and haemoglobin were estimated in blood. Urine samples were collected for 24 hours every other day before, during, and after the period of EGDN injection.

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