Effect of Haemophilus influenzae infection and moxalactam on platelet function in children.
AUTOR(ES)
Kaplan, S L
RESUMO
In a prospective randomized study, children with Haemophilus influenzae type b meningitis received moxalactam or ampicillin or chloramphenicol. Of 41 children, 6 had prolonged bleeding times (greater than 6 min), and 7 of 9 tested had abnormal platelet aggregation at hospital admission. At the end of therapy, no children in the ampicillin-chloramphenicol group, compared with 5 of 22 moxalactam-treated children (23%) (P = 0.08), had prolonged bleeding times (6.5 to 7.5 min). Our data suggest that H. influenzae meningitis and treatment with moxalactam may each have an effect on platelet function in children.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174755Documentos Relacionados
- Effect of cefotaxime or ceftriaxone treatment on nasopharyngeal Haemophilus influenzae type b colonization in children.
- A mucosal antibody response following systemic Haemophilus influenzae type B infection in children.
- Moxalactam pharmacokinetics in children.
- Turnover of nontypable Haemophilus influenzae in the nasopharynges of healthy children.
- Turnover of nonencapsulated Haemophilus influenzae in the nasopharynges of otitis-prone children.