Effect of Intrastrain Variation in the Amount of Capsular Polysaccharide on Genetic Transformation of Streptococcus pneumoniae: Implications for Virulence Studies of Encapsulated Strains
AUTOR(ES)
Weiser, Jeffrey N.
FONTE
American Society for Microbiology
RESUMO
The degrees of competence of opaque and transparent colony variants of Streptococcus pneumoniae were compared. The transparent variants were transformed at 9- to 670-fold-higher rates than the opaque variants, independent of the DNA incorporated, due to decreased expression of capsular polysaccharide. Genetic transformation, therefore, tends to select for a less-encapsulated subpopulation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=116567Documentos Relacionados
- Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone.
- Effect of genetic switching of capsular type on virulence of Streptococcus pneumoniae.
- Competence for genetic transformation in Streptococcus pneumoniae: molecular cloning of com, a competence control locus.
- Transformation of encapsulated Streptococcus pneumoniae.
- Genetic transformation in Streptococcus pneumoniae: molecular cloning and characterization of recP, a gene required for genetic recombination.
