Effect of perfusion of bile salts solutions into the oesophagus of hiatal hernia patients and controls.
AUTOR(ES)
Bachir, G S
RESUMO
Tests of the response to perfusion of the oesophagus were made in 54 patients divided into three groups. Group I consisted of patients with symptomatic hiatal hernia, group II hiatal hernia patients with peptic stricture, and group III normal individuals. Each individual oesophagus was perfused at a rate of 45-65 drops per minute over 25 minutes with six solutions: normal saline, N/10 HCl, taurine conjugates of bile salts in normal saline, taurine conjugates of bile salts in N/10 HCl, glycine conjugates of bile salts in normal saline, and taurine and glycine conjugates in a ratio of 1 to 2 in normal saline. It was found that acidified taurine solutions were more irritating than acid alone. With a 2mM/l solution of taurine in acid, symptoms are produced even in controls. With a 1 mM/l solution of the same conjugates, the majority of normal people feel slight heartburn or nothing, and therefore perfusion into the oesophagus of such a solution could be used as a test for oesophagitis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=470418Documentos Relacionados
- Hiatal Hernia and Short Oesophagus in Children
- The Treatment of Fibrous Stricture of the Oesophagus Associated with Hiatal Hernia
- Selective vagotomy of the canine oesophagus--a model for the treatment of hiatal hernia.
- Carcinoma of the cardia and thoracic oesophagus coexisting with and following sliding hiatal hernia and peptic stricture.
- Simultaneous measurement of intraluminal pressure and pH in the stomach and oesophagus: With special reference to the diagnosis of hiatal hernia and hiatal incompetence