Effect of Ultraviolet Light on Division and Deoxyribonucleic Acid Synthesis in Haemophilus influenzae
AUTOR(ES)
Kantor, George J.
RESUMO
The effects of ultraviolet (UV) light on cell morphology, deoxyribonucleic acid (DNA) synthesis, and protein synthesis in UV-sensitive and UV-resistant strains of Haemophilus influenzae were examined. Relatively low doses of UV induce lyses in the sensitive strains but not in the resistant mutant; however, UV temporarily blocks cell division of the resistant mutant, and elongated cells are formed after a period of incubation. Low doses of UV do not stop DNA synthesis in any of the strains examined; however, they do slow the rate of DNA synthesis in a manner consistent with the model correlating the kinetics of postirradiation DNA synthesis with the cell's ability to repair UV-induced DNA lesions. The data are not consistent with a model in which UV causes all DNA synthesis to stop for a time linearly dependent on dose.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=248030Documentos Relacionados
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