Effect of Vaccination with Refined Components of the Organism on Infection of Mice with Mycobacterium leprae

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton—the mycolyl-arabinogalactan-peptidoglycan complex—devoid of proteins is not protective.

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