Effects of Cycloheximide on the Response of Intestinal Mucosa to Cholera Enterotoxin
AUTOR(ES)
Kimberg, Daniel V.
RESUMO
Prior studies have indicated that effects of cholera enterotoxin (CT) on the small intestine are delayed in onset and involve an interaction with adenyl cyclase in the mucosa. It has also been shown that the administration of cycloheximide to rabbits in doses which inhibit crypt cell mitoses (20 mg/kg), diminishes CT-induced fluid production in jejunal loops. These latter studies have been interpreted as indications that CT-related intestinal secretion is a crypt cell function and that it is mediated by a CT-induced protein.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=302401Documentos Relacionados
- Development of Intestinal Adenyl Cyclase and Its Response to Cholera Enterotoxin
- Intestinal myoelectric activity in response to live Vibrio cholerae and cholera enterotoxin.
- Effect of Cholera Enterotoxin on Ion Transport across Isolated Ileal Mucosa
- In Vivo Suppression of the Immune Response to Alloantigen by Cholera Enterotoxin
- Binding of cholera toxin to pig intestinal mucosa glycosphingolipids: relationship with the ABO blood group system.