Effects of Ionenes on Interferon Induction by Poly(Inosinic Acid)·Poly(Cytidylic Acid)

AUTOR(ES)

De Clercq, Erik

RESUMO

Depending on the spacing of their positive charges, ionenes, a class of quaternary ammonium polymers, increased the interferon-inducing activity of poly(inosinic acid)·poly(cytidylic acid) in mouse L-929 cells, whereas they did not enhance poly(inosinic acid)·poly(cytidylic acid) induced interferon production in primary rabbit kidney and human skin fibrolast cells.

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