Effects of meningococcal and Escherichia coli capsular polysaccharides on human and dog platelet aggregation in vitro.
AUTOR(ES)
Johnsson, H
RESUMO
Highly purified capsular polysaccharides from groups A, B, and C meningococci and from two strains of Escherichia coli did not aggregate human or dog platelets in vitro. Nor was there any detectable effect on platelet aggregation induced by adenosine diphosphate (ADP), epinephrine, or collagen. The results do not support the hypothesis that capsular polysaccharides are involved in the pathogenesis of thrombocytopenia often seen in severe infections with these bacteria.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=476083Documentos Relacionados
- Comparative Effects of Phenylbutazone, Naproxen and Flunixin Meglumine on Equine Platelet Aggregation and Platelet Factor 3 Availability in vitro
- Effect of Escherichia coli alpha-hemolysin on human peripheral leukocyte function in vitro.
- Effect of Escherichia coli alpha-hemolysin on human peripheral leukocyte viability in vitro.
- Human platelet aggregation is initiated by peripheral blood mononuclear cells exposed to bacterial lipopolysaccharide in vitro.
- Staphylococcus aureus susceptibility to thrombin-induced platelet microbicidal protein is independent of platelet adherence and aggregation in vitro.
