Efficacy of Sulfamethoxypyridazine in a Murine Model of Pneumocystis carinii Pneumonia
AUTOR(ES)
Bartlett, Marilyn S.
FONTE
American Society for Microbiology
RESUMO
Sulfamethoxazole is the component of co-trimoxazole responsible for its efficacy against Pneumocystis carinii pneumonia, but this drug is associated with frequent adverse effects. Sulfamethoxypyridazine is significantly more effective than sulfamethoxazole against a murine model of P. carinii and might be a candidate for testing in infected patients.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105571Documentos Relacionados
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