Endorphins may function in heat adaptation.
AUTOR(ES)
Holaday, J W
RESUMO
Administration of the opiate antagonist naloxone to rats after acute or chronic heat exposure precipitates an increase in colonic temperature, an increase in escape attempts, and a decrease in body weight. These changes are accompanied by signs associated with hyperthermia such as salivation, diarrhea, and an abnormal extended posture. Although brain endorphin involvement is possible, hypophysectomy diminishes the intensity and magnitude of these naloxone effects, indicating that the naloxone effect in intact animals may be due to a functional antagonism of pituitary endorphins. These observations suggest that endorphins attenuate physiological responses to thermal and noxious stimuli triggered in common neuroanatomical pathways by heat.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=392678Documentos Relacionados
- Endorphins may function in heat adaptation
- Heat resistance of bacterial spores correlated with protoplast dehydration, mineralization, and thermal adaptation.
- Cultural versus genetic adaptation.
- Genetic variability for stomatal conductance in Pima cotton and its relation to improvements of heat adaptation.
- Molecular aspects fo bovine adaptation.