Endothelial Colony-forming Cells from Preterm Infants Are Increased and More Susceptible to Hyperoxia

AUTOR(ES)

Baker, Christopher D.

FONTE

American Thoracic Society

RESUMO

Rationale: Preterm birth and hyperoxic exposure increase the risk for bronchopulmonary dysplasia (BPD), a chronic lung disease characterized by impaired vascular and alveolar growth. Endothelial progenitor cells, such as self-renewing highly proliferative endothelial colony-forming cells (ECFCs), may participate in vascular repair. The effect of hyperoxia on ECFC growth is unknown.

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