Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil

AUTOR(ES)

Miranda, Karla R, Dias, Mariana F, Guimarães, Priscilla LS, Boente, Renata F, Pauer, Heidi, Ramos, Priscila Z, Falcão, Laís S, Ferreira, Eliane de O, Balassiano, Ilana T, Ferreira, Livia Q, Santos-Filho, Joaquim dos, Paula, Geraldo R de, Antunes, Eduardo NF, Avelar, Katia ES, Domingues, Regina MCP

FONTE

Memórias do Instituto Oswaldo Cruz

DATA DE PUBLICAÇÃO

2008-11

RESUMO

The presence of enterotoxigenic Bacteroides fragilis and nontoxigenic B. fragilis (NTBF) among 109 strains isolated from 1980-2008 in Brazil were investigated by PCR. One strain, representing 0.9% of the total analyzed strains, harbored the bft gene which was identified as bft-1 isoform based on PCR-RFLP and sequencing. Forty-nine strains (44.9%) exhibited the NTBF pattern III which possesses the flanking region required for pathogenicity island acquisition in which the bftgene is codified. These data reinforce the potential of B. fragilis as an emerging enteropathogen in our country.

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