Enzymatic basis of thiol-stimulated secretion of porphyrins by Escherichia coli.

AUTOR(ES)

Javor, G T

RESUMO

1-Thioglycerol (TG) stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. Here the levels of delta-aminolevulinate biosynthetic enzymes in untreated and TG-treated E. coli THU and PUC2 (a mutant of THU which overproduces porphyrins in the presence of thiols) cells were determined. TG treatment elevated the activity of glutamyl-tRNA reductase in both strains. The increased activity was not caused by activation of preexisting enzymes by thiols or by oxidizing agents but was dependent on new protein synthesis.

Documentos Relacionados

• Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli.
• Thiol-sensitive promoters of Escherichia coli.
• Thiol-sensitive genes of Escherichia coli.
• ENZYMATIC BASIS OF RESISTANCE TO AUREOMYCIN III. Escherichia coli: Inhibition by Aureomycin of Protein-Stimulated Electron Transport in
• Synthesis and secretion of hemolysin by Escherichia coli.