Estimating the posterior probability that genome-wide association findings are true or false

AUTOR(ES)
FONTE

Oxford University Press

RESUMO

Motivation: A limitation of current methods used to declare significance in genome-wide association studies (GWAS) is that they do not provide clear information about the probability that GWAS findings are true of false. This lack of information increases the chance of false discoveries and may result in real effects being missed.

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