Estimation of the low-density (beta) lipoproteins of serum in health and disease using large molecular weight dextran sulphate

AUTOR(ES)

Walton, K. W.

RESUMO

Studies have been made of the factors affecting the specificity of the interaction between high molecular weight dextran sulphate and low-density lipoproteins, both in pure solution and in serum. The results have been used in the development of a simple assay method for the serum concentration of low-density lipoproteins in small volumes of serum. The results obtained by this assay procedure have been found to correlate acceptably with parallel estimations of low-density lipoproteins by an ultracentrifugal technique and by paper electrophoresis.

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