Estudo comparativo entre a cola de fibrina e o plasma rico em plaquetas em enxertos cutâneos em cães / Comparative study between the fibrin glue and platelet-rich plasma on skin grafts in dogs

AUTOR(ES)
DATA DE PUBLICAÇÃO

2010

RESUMO

Skin grafts in dogs are mainly used in large skin loss in the distal regions of limbs. Fibrin glue and platelet-rich plasma act as adjuvants in the healing skin. The aim of this study was to compare fibrin glue (Tissucol ) and platelet-rich plasma on skin grafts, full thickness mesh in dogs. Were used 18 dogs divided into two groups, fibrin glue (CF) and platelet-rich plasma (PRP). In all animals we performed a skin graft from 3x3 cm full-thickness mesh. In the left limb was placed between the graft and receptor bed, the biomaterial each in their group, and the right limb served as control. All animals were clinically evaluate 48 hours until the fourteenth day, through the variables: exudation, color, edema and cosmetic appearance; and three of them were evaluate histologically in the third, seventh and fourteenth days postoperatively through the variables autolysis, fibroblasts , collagen, granulation tissue, adhesion-integrating microscopic and acute inflammation. By testing statistically significant (P <0.05), it was concluded that fibrin glue group was clinically superior to the group platelet-rich plasma when used in full thickness skin grafts in dogs.

ASSUNTO(S)

fibrin glue cola de fibrina ciências da saúde skin grafts plasma rico em plaquetas dogs platelet-rich plasma enxerto cutâneo

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