Estudo fitoquimico de leguminosas : Harleyodendron Unifoliolatum e Holocalyx balansae. Isolamento, determinação estrutural e atividade biologica / Phytochemical analysis of leguminosas : Harleyodendron Unifoliolatum Cowan e Holocalyx Balansae Micheli. Isolation, structural elucidation and biological activities
AUTOR(ES)
Andre Camargo de Oliveira
DATA DE PUBLICAÇÃO
2005
RESUMO
The phytochemical study of roots extracts from Harleyodendron unifoliolatum and Holocalyx balansae, both belonging to the family Leguminosae, resulted in the isolation of nine isoflavonoids (four pterocarpans, two isoflavans and three isoflavanones) and one phytosteroid being that seven isoflavonoids are now described for the first time. The molecular structures were elucidated through spectra analysis (UV, IV, NMR and HREIMS) when NMR spectroscopy was explored trough H NMR, C NMR (including DEPT 90° and 135°), 2D-NMR (gCOSY, HSQC, gHMBC) and NOESY-1D experiments. The antimicrobial activity of the isoflavonoids (1-9) was screened through bioautography against eight species of fungi (Alternaria alternata, Aspergillus fumigatus, Aspergillus niger, Candida albicans, Cladosporium cladosporioides, Fusarium oxysporum, Penicillium funiculosum and Rhizopus orizae) and six species of bacteria (Bacillus subtilis, Escherichia coli, Micrococcus Iuteus, SalmoneIla tiphymurium, Staphilococcus aureus and Streptococcus mutans), when it was found that 1 was active against fungi Alternaria alternata and Penicillium funiculosum; 2 was active against bacteria Escherichia coli and fungus Aspergillus niger; 3 and 6 were active against bacteria Bacillus subtilis and fungi Aspergillus fumigatus and Rizophus orizae, 5 and 7 was active against bacteria Bacillus subtilis and Staphilococcus aureus and fungus Penicillium funiculosum. The flavonoid profile furnished by the plant species analysed in this work corroborate with their allocation in the tribe Swartizieae as it has been recently propose by A.M.G.A. Tozzi based on morphology.
ASSUNTO(S)
leguminosas fitoquimica leguminosas atividade biologica biological activity phytochemical
ACESSO AO ARTIGO
http://libdigi.unicamp.br/document/?code=vtls000365773Documentos Relacionados
- PHYTOCHEMICAL STUDY OF HANCORNIA SPECIOSA: isolation, structural determination and biological activity
- ESTUDO FITOQUÍMICO DE HANCORNIA SPECIOSA GOMES: isolamento, determinação estrutural e atividade biológica
- Diterpenos de Myrocarpus frondosus Allemão : isolamento, determinação estrutural e atividade biologica
- Estudo fitoquimico de Poecilanthe parviflora Benth. e Lonchocarpus atropurpureus Benth. (Leguminosae) isolamento, determinação estrutural e atividade biologica
- Estudo fitoquimico de algumas especies de Eleocharis R. Br. (Cyperaceae) : isolamento, elucidação estrutural e atividade biologica
