Ethylene Oxide Gaseous Sterilization: II. Influence of Method of Humidification
AUTOR(ES)
Ernst, Robert R.
RESUMO
The duration of the equilibration period between admission of water vapor and subsequent introduction of gaseous ethylene oxide to an evacuated sterilizer chamber was studied with respect to its effect on the inactivation of spores of Bacillus subtilis var. niger under simulated practical conditions. Introduction of a water-adsorbing cotton barrier between the spores and an incoming gas mixture of water vapor and ethylene oxide caused a marked increase in the observed thermochemical death time of the spore populations. This effect was negated by admission of water vapor one or more minutes prior to introduction of ethylene oxide gas. Increases in temperature and relative humidity of the system promoted passage of water vapor through the cotton barriers and diminished their effect.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1057871Documentos Relacionados
- Microbiological Aspects of Ethylene Oxide Sterilization: II. Microbial Resistance to Ethylene Oxide
- Ethylene Oxide Gaseous Sterilization: I. Concentration and Temperature Effects
- Microbiological Aspects of Ethylene Oxide Sterilization: IV. Influence of Thickness of Polyethylene Film on the Sporicidal Activity of Ethylene Oxide
- Microbiological Aspects of Ethylene Oxide Sterilization: I. Experimental Apparatus and Methods
- Microbiological Aspects of Ethylene Oxide Sterilization: III. Effects of Humidity and Water Activity on the Sporicidal Activity of Ethylene Oxide
