Evaluation of five commercial tests for detection of immunoglobulin M antibodies to human parvovirus B19.
AUTOR(ES)
Bruu, A L
RESUMO
The following commercial tests for detection of immunoglobulin M antibodies to human parvovirus B19 were evaluated: Ideia Parvovirus B19-IgM, MRL Diagnostics Human Parvovirus B19 IgM ELISA, Parvoscan-B19, and Biotrin Parvo B19 IgM EIA and IF. A total of 203 serum specimens from patients who probably have current B19 infections or have other viral infections and sera with rheumatoid factor were investigated. Between 75 and 79 of 102 serum samples from patients thought to have current B19 infections yielded positive results with the different tests. Ideia had the highest specificity (94.8%), while Parvoscan showed a specificity of only 70.1%. Our evaluation results show that Ideia, MRL, and Biotrin EIA and IF can be recommended for diagnostic purposes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=228166Documentos Relacionados
- Evaluation of a synthetic-peptide enzyme-linked immunosorbent assay for immunoglobulin M to human parvovirus B19.
- Aseptic meningitis caused by human parvovirus B19.
- Evaluation of serological assays for identification of parvovirus B19 immunoglobulin M.
- Evaluation of commercial enzyme linked immunosorbent assay for detection of B19 parvovirus IgM and IgG.
- Characterization of a nested polymerase chain reaction assay for detection of parvovirus B19.
