Evaluation of the Ciba Corning Biotrack 512 coagulation monitor for the control of oral anticoagulation.

AUTOR(ES)

Jennings, I

RESUMO

The Ciba Corning Biotrack 512 coagulation monitor requires a minimal degree of technical expertise to operate, and is already in use for near-patient testing. This study evaluated the monitor for possible use in decentralised control of oral anticoagulant treatment. The monitor compared well with Manchester Reagent, suggesting that it could be used in areas where this thromboplastin is used for centralised control. The inability of the monitor to allow for locally determined geometric mean normal prothrombin times in the calculation of the International Normalised Ratio (INR), and possibly the high International Sensitivity Index (ISI) of the thromboplastin used with the monitor, resulted in poor comparability with some other thromboplastins, particularly Thrombotest. These problems need to be addressed if the monitor is to be used for decentralised anticoagulant control.

Documentos Relacionados

• Long-term anticoagulation. Indications and management.
• Photoselective vaporization of the prostate in men with a history of chronic oral anti-coagulation
• Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism.
• Evaluation of computerized decision support for oral anticoagulation management based in primary care.
• Introduction of computer assisted control of oral anticoagulation in general practice.