Evidence for cross-pathway regulation of metabolic gene expression in plants.
AUTOR(ES)
Guyer, D
RESUMO
In Arabidopsis thaliana, blocking histidine biosynthesis with a specific inhibitor of imidazoleglycerol-phosphate dehydratase caused increased expression of eight genes involved in the biosynthesis of aromatic amino acids, histidine, lysine, and purines. A decrease in expression of glutamine synthetase was also observed. Addition of histidine eliminated the gene-regulating effects of the inhibitor, demonstrating that the changes in gene expression resulted from histidine-pathway blockage. These results show that plants are capable of cross-pathway metabolic regulation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=41834Documentos Relacionados
- Cross-Pathway Regulation: Tryptophan-Mediated Control of Histidine and Arginine Biosynthetic Enzymes in Neurospora crassa
- Cross-Pathway Regulation in Saccharomyces cerevisiae: Activation of the Proline Utilization Pathway by Gal4p In Vivo
- Cross-Pathway Regulation: Histidine-Mediated Control of Histidine, Tryptophan, and Arginine Biosynthetic Enzymes in Neurospora crassa
- Mutations in the Saccharomyces Cerevisiae Opi3 Gene: Effects on Phospholipid Methylation, Growth and Cross-Pathway Regulation of Inositol Synthesis
- Saccharomyces Cerevisiae Cho2 Mutants Are Deficient in Phospholipid Methylation and Cross-Pathway Regulation of Inositol Synthesis
