Evidence for H-2-linked control of retrovirus production in Friend virus-induced tumor cell lines.
AUTOR(ES)
Wolfe, J H
RESUMO
In Friend leukemia virus-induced tumor cell lines derived from mice congenic with respect to the H-2 complex, most cell lines expressing the H-2k haplotype continuously produced infectious exogenous virus in culture, whereas most cell lines expressing the H-2b or H-2d haplotype stopped producing virus during in vitro passage. This apparent H-2-linked control of virus production did not appear to be the result of alteration of the provirus or resistance to superinfection. The implications of this finding with respect to virus-induced leukemogenesis are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=252984Documentos Relacionados
- Variation in p30-related proteins in gross virus-induced tumor cell lines derived from H-2 congenic mice.
- Natural killer cell suppression of Friend virus-induced preleukemic hemopoietic stem cells.
- Virus-Induced Cell Motility
- Erythrocytic maturation of (Friend) virus-induced leukemic cells in spleen clones.
- Molecular Pathways in Virus-Induced Cytokine Production
