Expression of Vibrio vulnificus Capsular Polysaccharide Inhibits Biofilm Formation

AUTOR(ES)

Joseph, Lavin A.

FONTE

American Society for Microbiology

RESUMO

Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.

Documentos Relacionados

• Differential Expression of Vibrio vulnificus Capsular Polysaccharide
• Immunogenicity of Vibrio vulnificus capsular polysaccharides and polysaccharide-protein conjugates.
• Identification of a Group 1-Like Capsular Polysaccharide Operon for Vibrio vulnificus
• Purification and determination of the structure of capsular polysaccharide of Vibrio vulnificus M06-24.
• Identification of Genetic Loci Required for Capsular Expression in Vibrio vulnificus†