Failure to Detect Cyclic 3′, 5′-Adenosine Monophosphate in Healthy and Crown Gall Tumorous Tissues of Vicia faba1
AUTOR(ES)
Niles, Richard M.
RESUMO
Attempts were made to provide proof for the occurrence of cyclic 3′,5′-adenosine monophosphate in healthy and crown gall tissues of Vicia faba. Although our purified extracts gave positive readings in the Gilman binding assay for cyclic AMP, they were not digested by a specific cyclic 3′,5′-adenosine monophosphate phosphodiesterase from beef heart. The extracts were digested, however, by a partially purified cyclic nucleotide phosphodiesterase from carrot tissue, which attacks both cyclic 2′,3′- and 3′,5′-nucleotides. The data indicate that the substances detected in the V. faba extracts are perhaps cyclic 2′,3′-nucleotides, a possible RNA degradation product.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=367414Documentos Relacionados
- Cyclic 3', 5'-adenosine monophosphate phosphodiesterase mutants of Salmonella typhimurium.
- Control of Neurospora crassa morphology by cyclic adenosine 3', 5'-monophosphate and dibutyryl cyclic adenosine 3', 5'-monophosphate.
- Control and localization of rat adrenal cyclic guanosine 3', 5'-monophosphate. Comparison with adrenal cyclic adenosine 3', 5'-monophosphate.
- The content and metabolism of cyclic adenosine 3', 5'-monophosphate and cyclic guanosine 3', 5'-monophosphate in adenocarcinoma of the human colon.
- Failure of Cholera Enterotoxin to Alter Cyclic 3′, 5′- Adenosine Monophosphate-Mediated Responses in Toad Urinary Bladder