Fate of the thiomalate part after intramuscular administration of aurothiomalate in rheumatoid arthritis.
AUTOR(ES)
Jellum, E
RESUMO
The excretory fate and plasma level of thiomalate were studied after intramuscular administration of auro-14C-thiomalate to 3 patients with rheumatoid arthritis. The gold and the thiomalate parts separated in vivo, and the free thiomalate was excreted in the urine, rapidly at first and then slowly. After one day about 60% of the 14C-label had been recovered in the urine. The plasma level also declined rapidly. The results are in complete agreement with those previously described in animal experiments.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1000965Documentos Relacionados
- Fate of the gold and the thiomalate part after intramuscular administration of aurothiomalate to mice.
- Free thiomalate levels in rheumatoid arthritis.
- Failure of oral thiomalate to act as an alternative to intramuscular gold in rheumatoid arthritis.
- Intramuscular Administration of Steroids in Treatment of Rheumatoid Arthritis
- Biochemical indices of response to hydroxychloroquine and sodium aurothiomalate in rheumatoid arthritis.
