Foamy virus vectors.
AUTOR(ES)
Russell, D W
RESUMO
Human foamy virus (HFV) is a retrovirus of the spumavirus family. We have constructed vectors based on HFV that encode neomycin phosphotransferase and alkaline phosphatase. These vectors are able to transduce a wide variety of vertebrate cells by integration of the vector genome. Unlike vectors based on murine leukemia virus, HFV vectors are not inactivated by human serum, and they transduce stationary-phase cultures more efficiently than murine leukemia virus vectors. These properties, as well as their large packaging capacity, make HFV vectors promising gene transfer vehicles.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=189807Documentos Relacionados
- Improved Primate Foamy Virus Vectors and Packaging Constructs
- Psi- vectors: murine leukemia virus-based self-inactivating and self-activating retroviral vectors.
- Packaging Cell Lines for Simian Foamy Virus Type 1 Vectors
- Highly stable expression of a foreign gene from rabies virus vectors.
- cis-Acting Sequences Required for Simian Foamy Virus Type 1 Vectors
